SpiB regulates the expression of B-cell-related genes and increases the longevity of memory B cells

SpiB regulates the expression of B-cell-related genes and increases the longevity of memory B cells

Generation of memory B cells is one of the key features of adaptive immunity as they respond rapidly to re-exposure to the antigen and generate functional antibodies. Although the functions of memory B cells are becoming clearer, the regulation of memory B cell generation and maintenance is still no...

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Bibliographic Details
Main Authors: Shu Horiuchi, Takuya Koike, Hirofumi Takebuchi, Katsuaki Hoshino, Izumi Sasaki, Yuri Fukuda-Ohta, Tsuneyasu Kaisho, Daisuke Kitamura
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
memory B cell
germinal center B cell
SpiB
apoptosis
autophagy
humoral immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250719/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250719/full

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