Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells

Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells

Abstract Background Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. There are two subtypes, fusion gene-positive RMS (FP-RMS) and fusion gene-negative RMS (FN-RMS), depending on the presence of a fusion gene, either PAX3-FOXO1 or PAX7-FOXO1. These fusion genes are thought to...

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Bibliographic Details
Main Authors: Kazutaka Ouchi, Mitsuru Miyachi, Shigeki Yagyu, Ken Kikuchi, Yasumichi Kuwahara, Kunihiko Tsuchiya, Tomoko Iehara, Hajime Hosoi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cancer Cell International
Subjects:
HMGA2
Fusion-negative rhabdomyosarcoma
Netropsin
Online Access:http://link.springer.com/article/10.1186/s12935-020-01282-z

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http://link.springer.com/article/10.1186/s12935-020-01282-z

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