Agonist-Induced Ca<sup>2+</sup> Signaling in HEK-293-Derived Cells Expressing a Single IP<sub>3</sub> Receptor Isoform

Agonist-Induced Ca<sup>2+</sup> Signaling in HEK-293-Derived Cells Expressing a Single IP<sub>3</sub> Receptor Isoform

In mammals, three genes encode IP<sub>3</sub> receptors (IP<sub>3</sub>Rs), which are involved in agonist-induced Ca<sup>2+</sup> signaling in cells of apparently all types. Using the CRISPR/Cas9 approach for disruption of two out of three IP<sub>3</sub&g...

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Bibliographic Details
Main Authors: Ekaterina N. Kochkina, Elizaveta E. Kopylova, Olga A. Rogachevskaja, Nina P. Kovalenko, Natalia V. Kabanova, Polina D. Kotova, Marina F. Bystrova, Stanislav S. Kolesnikov
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
IP<sub>3</sub> receptor
Ca<sup>2+</sup> signaling
CRISP/Cas9
R-CEPIA1er
Ca<sup>2+</sup> imaging
Online Access:https://www.mdpi.com/2073-4409/13/7/562

Internet

https://www.mdpi.com/2073-4409/13/7/562

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