Chemotherapy‐induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer

Chemotherapy‐induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer

Abstract Ovarian cancer (OvCa) is the gynaecological disorder with the poorest prognosis due to the fast development of chemoresistance. We sought to connect chemoresistance and cancer cell‐derived extracellular vesicles (EV). The mechanisms of how chemoresistance is sustained by EV remained elusive...

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Bibliographic Details
Main Authors: Gerrit Hugendieck, Marcus Lettau, Svenja Andreas, Sabrina Neumann, Natalie Reinhardt, Philipp Arnold, Franziska Theilig, Lorenz Bastian, Christoph Rogmans, Jörg P. Weimer, Inken Flörkemeier, Daniela Wesch, Norbert Arnold, Nicolai Maass, Ottmar Janssen, Dirk Bauerschlag, Nina Hedemann
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of Extracellular Vesicles
Subjects:
ADAM17
ascites
chemoresistance
extracellular vesicles
ovarian cancer
Online Access:https://doi.org/10.1002/jev2.12338

Internet

https://doi.org/10.1002/jev2.12338

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