Cortisol controls endoplasmic reticulum stress and hypoxia dependent regulation of insulin receptor and related genes expression in HEK293 cells

Cortisol controls endoplasmic reticulum stress and hypoxia dependent regulation of insulin receptor and related genes expression in HEK293 cells

Objective. Glucocorticoids are important stress-responsive regulators of insulin-dependent metabolic processes realized through specific changes in genome function. The aim of this study was to investigate the impact of cortisol on insulin receptor and related genes expression in HEK293 cells upon i...

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Bibliographic Details
Main Authors: Minchenko Dmytro O., Khita Olena O., Viletska Yuliia M., Sliusar Myroslava Y., Rudnytska Olha V., Kozynkevych Halyna E., Bezrodnyi Borys H., Khikhlo Yevgen P., Minchenko Oleksandr H.
Format: Article
Language:English
Published: Sciendo 2024-01-01
Series:Endocrine Regulations
Subjects:
cortisol
tunicamycin
hypoxia
xbp1s
insulin receptor
irs2
insig2
dnajb9
hek293
Online Access:https://doi.org/10.2478/enr-2024-0001

Internet

https://doi.org/10.2478/enr-2024-0001

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