Cortisol controls endoplasmic reticulum stress and hypoxia dependent regulation of insulin receptor and related genes expression in HEK293 cells
Objective. Glucocorticoids are important stress-responsive regulators of insulin-dependent metabolic processes realized through specific changes in genome function. The aim of this study was to investigate the impact of cortisol on insulin receptor and related genes expression in HEK293 cells upon i...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2024-01-01
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Series: | Endocrine Regulations |
Subjects: | |
Online Access: | https://doi.org/10.2478/enr-2024-0001 |
Summary: | Objective. Glucocorticoids are important stress-responsive regulators of insulin-dependent metabolic processes realized through specific changes in genome function. The aim of this study was to investigate the impact of cortisol on insulin receptor and related genes expression in HEK293 cells upon induction the endoplasmic reticulum (ER) stress by tunicamycin and hypoxia. |
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ISSN: | 1336-0329 |