Catalyst- and solvent-free coupling of 2-methyl quinazolinones and 3-(trifluoroacetyl)coumarins: An environmentally benign access of quinazolinone derivatives

Catalyst- and solvent-free coupling of 2-methyl quinazolinones and 3-(trifluoroacetyl)coumarins: An environmentally benign access of quinazolinone derivatives

An environmentally benign highly atom-economic protocol for the construction of the CC bond has been developed under catalyst- and solvent-free conditions. This protocol involves the efficient coupling of 2-methyl quinazolinones with 3-(trifluoroacetyl)coumarins for the access of quinazolinone deri...

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Bibliographic Details
Main Authors: Xiaodan Chang, Liangxin Fan, Lijun Shi, Zhenliang Pan, Guoyu Yang, Cuilian Xu, Lulu Wu, Caixia Wang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Quinazolinone derivatives
Tertiary alcohols
Catalyst-free
Solvent-free
Antifungal activity
Online Access:http://www.sciencedirect.com/science/article/pii/S131961032300025X

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http://www.sciencedirect.com/science/article/pii/S131961032300025X

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