Cyclosporine Affects the Main Virulence Factors of <i>Cryptococcus neoformans</i> In Vitro

Cyclosporine Affects the Main Virulence Factors of <i>Cryptococcus neoformans</i> In Vitro

This study aimed to investigate the effects of cyclosporine on the morphology, cell wall structure, and secretion characteristics of <i>Cryptococcus neoformans</i>. The minimum inhibitory concentration (MIC) of cyclosporine was found to be 2 µM (2.4 µg/mL) for the H99 strain. Yeast cells...

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Bibliographic Details
Main Authors: Iara Bastos de Andrade, Dario Corrêa-Junior, Vinicius Alves, Maria Helena Galdino Figueiredo-Carvalho, Marcos Vinicius Santos, Marcos Abreu Almeida, Alessandro Fernandes Valdez, Leonardo Nimrichter, Rodrigo Almeida-Paes, Susana Frases
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Fungi
Subjects:
cyclosporine
<i>Cryptococcus neoformans</i>
capsule
calcineurin biology
virulence
Online Access:https://www.mdpi.com/2309-608X/9/4/487

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https://www.mdpi.com/2309-608X/9/4/487

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