Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies

Introduction Early diagnosis of systemic sclerosis (SSc) is important to start therapeutic interventions timely. Important risk factors for progression to SSc are the SSc-specific autoantibodies, of whom anti-centromere antibodies (ACA) and anti-topoisomerase I antibodies (ATA) are the most frequent...

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Main Authors: Cornelia F Allaart, Tom W J Huizinga, René E M Toes, Hans Ulrich Scherer, Jeska K de Vries-Bouwstra, Sophie I E Liem, Sam Neppelenbroek, Cynthia M Fehres, Brigitte A Wevers
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/9/1/e002827.full