T Cell Features in Glioblastoma May Guide Therapeutic Strategies to Overcome Microenvironment Immunosuppression

T Cell Features in Glioblastoma May Guide Therapeutic Strategies to Overcome Microenvironment Immunosuppression

Glioblastoma (GBM) is the most aggressive and lethal primary brain tumor, bearing a survival estimate below 10% at five years, despite standard chemoradiation treatment. At recurrence, systemic treatment options are limited and the standard of care is not well defined, with inclusion in clinical tri...

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Bibliographic Details
Main Authors: Agnese Losurdo, Antonio Di Muzio, Beatrice Claudia Cianciotti, Angelo Dipasquale, Pasquale Persico, Chiara Barigazzi, Beatrice Bono, Simona Feno, Federico Pessina, Armando Santoro, Matteo Simonelli
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
glioblastoma
T cells
tumor microenvironment
immune check-point blockade
vaccinations
adoptive cell therapy
Online Access:https://www.mdpi.com/2072-6694/16/3/603

Internet

https://www.mdpi.com/2072-6694/16/3/603

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