Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development

Abstract Testis development, including early embryonic gonad formation and late postnatal spermatogenesis, is essential for the reproduction of higher metazoans to generate fertile gametes, called sperm. We have previously reported that the polyubiquitin gene Ubb is required for fertility in both ma...

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Bibliographic Details
Main Authors: Bitnara Han, Byung-Kwon Jung, So-Hyun Park, Kyu Jin Song, Muhammad Ayaz Anwar, Kwon-Yul Ryu, Kwang Pyo Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00581-2