Direct Intra-Patient Comparison of Scaffold Protein-Based Tracers, [<sup>99m</sup>Tc]Tc-ADAPT6 and [<sup>99m</sup>Tc]Tc-(HE)<sub>3</sub>-G3, for Imaging of HER2-Positive Breast Cancer

Direct Intra-Patient Comparison of Scaffold Protein-Based Tracers, [<sup>99m</sup>Tc]Tc-ADAPT6 and [<sup>99m</sup>Tc]Tc-(HE)<sub>3</sub>-G3, for Imaging of HER2-Positive Breast Cancer

Previous Phase I clinical evaluations of the radiolabelled scaffold proteins [<sup>99m</sup>Tc]Tc-ADAPT6 and DARPin [<sup>99m</sup>Tc]Tc-(HE)<sub>3</sub>-G3 in breast cancer patients have demonstrated their safety and indicated their capability to discriminate bet...

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Bibliographic Details
Main Authors: Olga Bragina, Vladimir Chernov, Alexey Schulga, Elena Konovalova, Sophia Hober, Sergey Deyev, Jens Sörensen, Vladimir Tolmachev
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
radionuclide molecular imaging
clinical study
HER2
scaffold proteins
DARPin
ADAPT6
Online Access:https://www.mdpi.com/2072-6694/15/12/3149

Internet

https://www.mdpi.com/2072-6694/15/12/3149

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