Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension

Background : High circulating aldosterone levels stimulate myocardial fibrosis and left ventricular hypertrophy (LVH). However, it is not clear whether suppression of aldosterone directly contributes to LVH regression in hypertensive patients. Methods : The Aliskiren in Left Ventricular Hypertrophy...

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Bibliographic Details
Main Authors: Anne-Catherine Pouleur, Hajime Uno, Margaret F Prescott, Akshay Desai, Evan Appelbaum, Valentina Lukashevich, Beverly A Smith, Björn Dahlöf, Scott D Solomon
Format: Article
Language:English
Published: SAGE Publications 2011-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311414453