Epigenetic Regulation of Key Enzymes CYP7a1 and HMGCR Affect Hepatic Cholesterol Metabolism in Different Breeds of Piglets

Epigenetic Regulation of Key Enzymes CYP7a1 and HMGCR Affect Hepatic Cholesterol Metabolism in Different Breeds of Piglets

Liver is the place where cholesterol is synthesized, transported, secreted, and transformed, thus liver takes an irreplaceable role in cholesterol homeostasis. Hepatic cholesterol metabolism differs between breeds, yet the molecular mechanism is unclear. In this study Large White (LW) and Erhualian...

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Bibliographic Details
Main Authors: Xian Li, Hanyang Xiao, Xiaoqian Jian, Xiangyin Zhang, Hui Zhang, Yang Mu, Hua Wang, Shulin Chen, Rihua Cong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Veterinary Science
Subjects:
piglets
cholesterol metabolism
liver
epigenetic regulation
CYP7a1
HMGCR
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2020.00231/full

Internet

https://www.frontiersin.org/article/10.3389/fvets.2020.00231/full

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