Relationship between Serum Sirtuin 1 and Growth Hormone/Insulin-like Growth Factor 1 Concentrations in Children with Growth Hormone Deficiency and Idiopathic Short Stature

Relationship between Serum Sirtuin 1 and Growth Hormone/Insulin-like Growth Factor 1 Concentrations in Children with Growth Hormone Deficiency and Idiopathic Short Stature

Sirtuin 1 (SIRT1) inhibits growth hormone (GH) intracellular signaling for the insulin-like growth factor 1 (IGF-1) synthesis via the janus kinase (JAK)/signal transducer and activator of transcription proteins (STATs) pathway. The aim of this study was to compare SIRT1 concentrations in children wi...

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Bibliographic Details
Main Authors: Anna Fedorczak, Dorota Kowalik, Justyna Kopciuch, Ewa Głowacka, Katarzyna Mikołajczyk, Marcin Tkaczyk, Andrzej Lewiński, Renata Stawerska
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Biomedicines
Subjects:
growth hormone
growth hormone deficiency
non-GH-deficient children
short stature
JAK/STATs pathway
insulin-like growth factor 1
Online Access:https://www.mdpi.com/2227-9059/12/7/1433

Internet

https://www.mdpi.com/2227-9059/12/7/1433

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