Comprehensive Cis-Regulation Analysis of Genetic Variants in Human Lymphoblastoid Cell Lines

Genetic variants can influence the expression of mRNA and protein. Genetic regulatory loci such as expression quantitative trait loci (eQTLs) and protein quantitative trait loci (pQTLs) exist in several species. However, it remains unclear how human genetic variants regulate mRNA and protein express...

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Bibliographic Details
Main Authors: Ying Wang, Bo He, Yuanyuan Zhao, Jill L. Reiter, Steven X. Chen, Edward Simpson, Weixing Feng, Yunlong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00806/full