PANDA: Protein function prediction using domain architecture and affinity propagation

Abstract We developed PANDA (Propagation of Affinity and Domain Architecture) to predict protein functions in the format of Gene Ontology (GO) terms. PANDA at first executes profile-profile alignment algorithm to search against PfamA, KOG, COG, and SwissProt databases, and then launches PSI-BLAST ag...

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Bibliographic Details
Main Authors: Zheng Wang, Chenguang Zhao, Yiheng Wang, Zheng Sun, Nan Wang
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21849-1