Duplex High-Resolution Melting Assay for the Simultaneous Genotyping of IL28B rs12979860 and PNPLA3 rs738409 Polymorphisms in Chronic Hepatitis C Patients

Duplex High-Resolution Melting Assay for the Simultaneous Genotyping of IL28B rs12979860 and PNPLA3 rs738409 Polymorphisms in Chronic Hepatitis C Patients

Chronic hepatitis C (CHC) is a major burden for public health worldwide. Although newer direct-acting antivirals show good efficacy, their cost precludes their wide adoption in resource-limited regions. Thus, strategies are being developed to help identify patients with high susceptibility to respon...

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Bibliographic Details
Main Authors: Elena L. Enache, Anca Sin, Ligia Bancu, Christophe Ramière, Olivier Diaz, Patrice André, Liviu S. Enache
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:International Journal of Molecular Sciences
Subjects:
chronic hepatitis C
personalized diagnostics
duplex assay
high-resolution melting
interleukin 28B
patatin-like phospholipase domain containing 3 (PNPLA3)
single nucleotide polymorphism
Online Access:http://www.mdpi.com/1422-0067/16/9/22223

Internet

http://www.mdpi.com/1422-0067/16/9/22223

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