HigB1 Toxin in Mycobacterium tuberculosis Is Upregulated During Stress and Required to Establish Infection in Guinea Pigs

HigB1 Toxin in Mycobacterium tuberculosis Is Upregulated During Stress and Required to Establish Infection in Guinea Pigs

The extraordinary expansion of Toxin Antitoxin (TA) modules in the genome of Mycobacterium tuberculosis has received significant attention over the last few decades. The cumulative evidence suggests that TA systems are activated in response to stress conditions and are essential for M. tuberculosis...

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Bibliographic Details
Main Authors: Arun Sharma, Kalpana Sagar, Neeraj Kumar Chauhan, Balaji Venkataraman, Nidhi Gupta, Tannu Priya Gosain, Nikhil Bhalla, Ramandeep Singh, Amita Gupta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
HigBA1
toxin antitoxin loci
virulence
stringent response
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.748890/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.748890/full

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