Anthocyanins Protect Hepatocytes against CCl<sub>4</sub>-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and Excessive Proliferation of Kupffer Cells

Anthocyanins Protect Hepatocytes against CCl<sub>4</sub>-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and Excessive Proliferation of Kupffer Cells

This study examined the hepatoprotective and anti-inflammatory effects of anthocyanins from <i>Vaccinim myrtillus</i> (bilberry) fruit extract on the acute liver failure caused by carbon tetrachloride-CCl<sub>4</sub> (3 mL/kg, i.p.). The preventive treatment of the bilberry e...

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Bibliographic Details
Main Authors: Dejan Popović, Gordana Kocić, Vuka Katić, Aleksandra Zarubica, Ljubinka Janković Veličković, Vanja P. Ničković, Andrija Jović, Andrej Veljković, Vladimir Petrović, Violeta Rakić, Zorica Jović, Nataša Poklar Ulrih, Danka Sokolović, Marko Stojanović, Marko Stanković, Goran Radenković, Gordana R. Nikolić, Аzra Lukač, Aleksandar Milosavljević, Dušan Sokolović
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Antioxidants
Subjects:
carbon tetrachloride
anthocyanins
anti-inflammatory effects
kupffer cells
lipocalin-2
polyamine catabolism
Online Access:https://www.mdpi.com/2076-3921/8/10/451

Internet

https://www.mdpi.com/2076-3921/8/10/451

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