CNN-XG: A Hybrid Framework for sgRNA On-Target Prediction

As the third generation gene editing technology, Crispr/Cas9 has a wide range of applications. The success of Crispr depends on the editing of the target gene via a functional complex of sgRNA and Cas9 proteins. Therefore, highly specific and high on-target cleavage efficiency sgRNA can make this pr...

Full description

Bibliographic Details
Main Authors: Bohao Li, Dongmei Ai, Xiuqin Liu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/3/409