Pharmacokinetic/pharmacodynamic target attainment of intravenous β-lactam regimens against Gram-negative bacteria isolated in a Brazilian teaching hospital

Pharmacokinetic/pharmacodynamic target attainment of intravenous β-lactam regimens against Gram-negative bacteria isolated in a Brazilian teaching hospital

ABSTRACTINTRODUCTION: Monte Carlo simulations have been used for selecting optimal antibiotic regimens for treatment of bacterial infections. The aim of this study was to assess the pharmacokinetic and pharmacodynamic target attainment of intravenous β-lactam regimens commonly used to treat bloodstr...

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Bibliographic Details
Main Authors: Guilherme Henrique Furtado, Leandro Cardinal, Rodrigo Spineli Macedo, Juliana Oliveira Silva, Eduardo Alexandrino Medeiros, Joseph Levente Kuti, David Paul Nicolau
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2015-10-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Monte Carlo simulation
Pharmacodynamics
Gram-negative bacteria
Bloodstream infections
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500539&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500539&lng=en&tlng=en

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