Phenotypic and Genetic Evidence for a More Prominent Role of Blood Glucose than Cholesterol in Atherosclerosis of Hyperlipidemic Mice

Phenotypic and Genetic Evidence for a More Prominent Role of Blood Glucose than Cholesterol in Atherosclerosis of Hyperlipidemic Mice

Hyperlipidemia and type 2 diabetes (T2D) are major risk factors for atherosclerosis. <i>Apoe</i>-deficient (<i>Apoe</i><sup>−/−</sup>) mice on certain genetic backgrounds develop hyperlipidemia, atherosclerosis, and T2D when fed a Western diet. Here, we sought to...

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Bibliographic Details
Main Authors: Ashley M. Abramson, Lisa J. Shi, Rebecca N. Lee, Mei-Hua Chen, Weibin Shi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
atherosclerosis
dyslipidemia
hyperglycemia
quantitative trait locus
type 2 diabetes
Online Access:https://www.mdpi.com/2073-4409/11/17/2669

Internet

https://www.mdpi.com/2073-4409/11/17/2669

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