Evidence of kidney injury in preeclampsia: Increased maternal and urinary levels of NGAL and KIM-1 and their enhanced expression in proximal tubule epithelial cells

Evidence of kidney injury in preeclampsia: Increased maternal and urinary levels of NGAL and KIM-1 and their enhanced expression in proximal tubule epithelial cells

Background and objectiveProteinuria and glomerular endotheliosis are characteristics of glomerular injury in preeclampsia, a hypertensive disorder in human pregnancy. Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) are biomarkers of acute/chronic renal tubule i...

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Bibliographic Details
Main Authors: Yuping Wang, Yang Gu, Xin Gu, Danielle B. Cooper, David F. Lewis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Medicine
Subjects:
kidney injury
NGAL
KIM-1
pregnancy
preeclampsia
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1130112/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1130112/full

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