Isorhynchophylline alleviates cartilage degeneration in osteoarthritis by activating autophagy of chondrocytes

Abstract Context Osteoarthritis is a common degenerative disease, the cause of it is still unknown, and the treatment mainly focuses on improving symptoms. Studies have found that Isorhynchophylline (Isorhy) has antioxidant, anti-inflammatory, antiproliferative and neuroprotective effects. Objective...

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Bibliographic Details
Main Authors: Jieyun Jiang, Jin Li, Chenwei Xiong, Xindie Zhou, Ting Liu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03645-4