Resveratrol relieves myocardial ischemia–reperfusion injury through inhibiting AKT nitration modification

Resveratrol relieves myocardial ischemia–reperfusion injury through inhibiting AKT nitration modification

Objective The aim of this study was to clarify whether Protein kinase B (PKB)/AKT is nitrated in myocardial ischemia and reperfusion injury (MIRI) resveratrol (RSV)’s protective effect during this process.Methods We blocked blood flow of the left coronary artery (LAD) of mice and used H9c2 cells und...

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Bibliographic Details
Main Authors: Lei Li, Jiantao Wang, Dandan Zhang, Li Deng, Xudong Zhao, Chunqing Wang, Xianliang Yan, Shuqun Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Redox Report
Subjects:
AKT
nitration
myocardial ischemia–reperfusion
oxidative stress
N-methyl-D-aspartic acid receptor (NMDAR)
‌neuronal nitric oxide synthase (nNOS)
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2420564

Internet

https://www.tandfonline.com/doi/10.1080/13510002.2024.2420564

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