Development of a rapid and highly sensitive nucleic acid-based diagnostic test for schistosomes, leveraging on identical multi-repeat sequences

Development of a rapid and highly sensitive nucleic acid-based diagnostic test for schistosomes, leveraging on identical multi-repeat sequences

IntroductionSchistosomiasis (Bilharzia), a neglected tropical disease caused by Schistosoma parasites, afflicts over 240 million people globally, disproportionately impacting Sub-Saharan Africa. Current diagnostic tests, despite their utility, suffer from limitations like low sensitivity. Polymerase...

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Bibliographic Details
Main Authors: Ombeni Ally, Bernard N. Kanoi, Shwetha Kamath, Clement Shiluli, Eric M. Ndombi, Maurice Odiere, Gerald Misinzo, Steven Ger Nyanjom, Chunduri Kiran Kumar, Lucy Ochola, Srinivasa Raju Lolabattu, Jesse Gitaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Parasitology
Subjects:
Schistosoma mansoni
Schistosoma haematobium
schistosomiasis
PCR
qPCR
IMRS
Online Access:https://www.frontiersin.org/articles/10.3389/fpara.2024.1361493/full

Internet

https://www.frontiersin.org/articles/10.3389/fpara.2024.1361493/full

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