Introduction of a Polyethylene Glycol Linker Improves Uptake of <sup>67</sup>Cu-NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide in Melanoma

Introduction of a Polyethylene Glycol Linker Improves Uptake of <sup>67</sup>Cu-NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide in Melanoma

The aim of this study was to evaluate the effect of linker on tumor targeting and biodistribution of <sup>67</sup>Cu-NOTA-PEG<sub>2</sub>Nle-CycMSH<sub>hex</sub> {<sup>67</sup>Cu-1,4,7-triazacyclononane-1,4,7-triyl-triacetic acid-polyethylene glycol-Nl...

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Bibliographic Details
Main Authors: Zheng Qiao, Jingli Xu, Darrell R. Fisher, Rene Gonzalez, Yubin Miao
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
<sup>67</sup>Cu-NOTA
lactam-cyclized
alpha-melanocyte-stimulating hormone
melanocortin-1 receptor
melanoma treatment
Online Access:https://www.mdpi.com/2072-6694/15/10/2755

Internet

https://www.mdpi.com/2072-6694/15/10/2755

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