The influence of MK-801, glutamate and glycine via the modulation of N-methyl-D-aspartate receptors on isolated rat heart

The influence of MK-801, glutamate and glycine via the modulation of N-methyl-D-aspartate receptors on isolated rat heart

N-methyl-D-aspartate (NMDA) receptors belong to the group of inotropic glutamate receptors, which are found in rat cardiomyocytes.Aim. To evaluate the influence of a non-competitive antagonist of NMDA-receptors — МК-801, separately or in combination with glutamate and/or glycine, on cardiodynamic pa...

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Bibliographic Details
Main Authors: N. S. Govorushkina, S. B. Bolevich, V. Jakovlevich, B. I. Tachieva, S. S. Bolevich, A. S. Orlova, M. A. Fokina, A. B. Saltykov, E. M. Morozova, N. V. Samburova, M. N. Vukolova, E. B. Tezikov
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2020-03-01
Series:Сеченовский вестник
Subjects:
n-methyl-d-aspartate (nmda) receptors
glutamate receptors
mk-801
oxidative stress
glutamate
glycine
isolated heart
Online Access:https://www.sechenovmedj.com/jour/article/view/171

Internet

https://www.sechenovmedj.com/jour/article/view/171

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