Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against <i>Hymenolepis nana</i> in Experimentally-Infected Rats

Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against <i>Hymenolepis nana</i> in Experimentally-Infected Rats

Hymenolepiasis represents a parasitic infection of common prevalence in pediatrics with intimidating impacts, particularly amongst immunocompromised patients. The present work aimed to snowball the curative outcomes of the current mainstay of hymenolepiasis chemotherapy, praziquantel (PRZ), through...

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Bibliographic Details
Main Authors: Waleed M. Arafa, Mohammed H. Elkomy, Heba M. Aboud, Mona Ibrahim Ali, Samah S. Abdel Gawad, Shawky M. Aboelhadid, Emad A. Mahdi, Izzeddin Alsalahat, Heba Abdel-Tawab
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
praziquantel
<i>Hymenolepis nana</i>
polymeric mixed micelles
oral targeting
Box-Behnken design
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/14/10/2023

Internet

https://www.mdpi.com/1999-4923/14/10/2023

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