Visualizing GABA transporters in vivo: an overview of reported radioligands and future directions

Visualizing GABA transporters in vivo: an overview of reported radioligands and future directions

Abstract By clearing GABA from the synaptic cleft, GABA transporters (GATs) play an essential role in inhibitory neurotransmission. Consequently, in vivo visualization of GATs can be a valuable diagnostic tool and biomarker for various psychiatric and neurological disorders. Not surprisingly, in rec...

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Bibliographic Details
Main Authors: Niels Knippenberg, Matthias Bauwens, Olaf Schijns, Govert Hoogland, Alexandru Florea, Kim Rijkers, Thomas J. Cleij, Kasper Eersels, Bart van Grinsven, Hanne Diliën
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:EJNMMI Research
Subjects:
GABA
PET imaging
GABA transporter
GAT radioligand
GAT inhibitor
Online Access:https://doi.org/10.1186/s13550-023-00992-5

Internet

https://doi.org/10.1186/s13550-023-00992-5

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