The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1
RNA polymerase II (PolII) transcribes RNA within a chromatin context, with nucleosomes acting as barriers to transcription. Despite these barriers, transcription through chromatin in vivo is highly efficient, suggesting the existence of factors that overcome this obstacle. To increase the resolution...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/02042 |