Phenotypic and Genotypic Comparison of a Live-Attenuated Genotype I Japanese Encephalitis Virus SD12-F120 Strain with Its Virulent Parental SD12 Strain

Phenotypic and Genotypic Comparison of a Live-Attenuated Genotype I Japanese Encephalitis Virus SD12-F120 Strain with Its Virulent Parental SD12 Strain

The phenotypic and genotypic characteristics of a live-attenuated genotype I (GI) strain (SD12-F120) of Japanese encephalitis virus (JEV) were compared with its virulent parental SD12 strain to gain an insight into the genetic changes acquired during the attenuation process. SD12-F120 formed smaller...

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Bibliographic Details
Main Authors: Muhammad Naveed Anwar, Xin Wang, Muddassar Hameed, Abdul Wahaab, Chenxi Li, Mona Sharma, Linlin Pang, Muhammad Irfan Malik, Ke Liu, Beibei Li, Yafeng Qiu, Jianchao Wei, Zhiyong Ma
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
Japanese encephalitis virus
attenuation
virulence
vaccine
genotype
amino acid substitution
Online Access:https://www.mdpi.com/1999-4915/12/5/552

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https://www.mdpi.com/1999-4915/12/5/552

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