Monoamine Oxidase Inhibition by Major Tanshinones from <i>Salvia miltiorrhiza</i> and Selective Muscarinic Acetylcholine M<sub>4</sub> Receptor Antagonism by Tanshinone I

Monoamine Oxidase Inhibition by Major Tanshinones from <i>Salvia miltiorrhiza</i> and Selective Muscarinic Acetylcholine M<sub>4</sub> Receptor Antagonism by Tanshinone I

Monoamine oxidases (MAOs) and muscarinic acetylcholine receptors (mAChRs) are considered important therapeutic targets for Parkinson’s disease (PD). Lipophilic tanshinones are major phytoconstituents in the dried roots of <i>Salvia miltiorrhiza</i> that have demonstrated neuroprotective...

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Bibliographic Details
Main Authors: Ritu Prajapati, Se Eun Park, Su Hui Seong, Pradeep Paudel, Fazlin Mohd Fauzi, Hyun Ah Jung, Jae Sue Choi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
tanshinone I
Parkinson’s disease
monoamine oxidase inhibition
molecular docking
M<sub>4</sub> receptor antagonist
Online Access:https://www.mdpi.com/2218-273X/11/7/1001

Internet

https://www.mdpi.com/2218-273X/11/7/1001

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