Thrombospondin-1 induction and VEGF reduction by proteasome inhibition

Thrombospondin-1 induction and VEGF reduction by proteasome inhibition

The present study focuses on investigating the expression of thrombospondin-1 (TSP-1), a natural inhibitor of neovascularization. Immunofluorescent staining was used to detect the expression of TSP-1 in rabbit corneal tissue with vascularization induced by limbectomy. TSP-1 was detected in healthy a...

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Bibliographic Details
Main Authors: Fawzia Bardag-Gorce, Carter Hoffman, Imara Meepe, Monica Ferrini, Richard H. Hoft, Joan Oliva, Yutaka Niihara
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Heliyon
Subjects:
Corneal vascularization
Proteasome inhibition
Thrombospondin-1
VEGF
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023006047

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http://www.sciencedirect.com/science/article/pii/S2405844023006047

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