TerC proteins function during protein secretion to metalate exoenzymes

Abstract Cytosolic metalloenzymes acquire metals from buffered intracellular pools. How exported metalloenzymes are appropriately metalated is less clear. We provide evidence that TerC family proteins function in metalation of enzymes during export through the general secretion (Sec-dependent) pathw...

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Bibliographic Details
Main Authors: Bixi He, Ankita J. Sachla, John D. Helmann
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41896-1