Impaired training-induced angiogenesis process with loss of pericyte-endothelium interactions is associated with an abnormal capillary remodelling in the skeletal muscle of COPD patients

Impaired training-induced angiogenesis process with loss of pericyte-endothelium interactions is associated with an abnormal capillary remodelling in the skeletal muscle of COPD patients

Abstract Chronic obstructive pulmonary disease (COPD) is associated with exercise intolerance and limits the functional gains in response to exercise training in patients compared to sedentary healthy subjects (SHS). The blunted skeletal muscle angiogenesis previously observed in COPD patients has b...

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Bibliographic Details
Main Authors: Léo Blervaque, Emilie Passerieux, Pascal Pomiès, Matthias Catteau, Nelly Héraud, Marine Blaquière, François Bughin, Bronia Ayoub, Nicolas Molinari, Jean-Paul Cristol, Antonia Perez-Martin, Jacques Mercier, Maurice Hayot, Fares Gouzi
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Respiratory Research
Subjects:
COPD
Capillaries
Angiogenesis
Skeletal muscle
Exercise training
Online Access:https://doi.org/10.1186/s12931-019-1240-6

Internet

https://doi.org/10.1186/s12931-019-1240-6

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