Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway

Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway

Diabetes-associated bone complications lead to fragile bone mechanical strength and osteoporosis, aggravating the disease burden of patients. Advanced evidence shows that chronic hyperglycemia and metabolic intermediates, such as inflammatory factor, reactive oxygen species (ROS), and advanced glyca...

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Bibliographic Details
Main Authors: Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
diabetes
bone loss
primary cilia
Icariin
ROS
Online Access:https://www.mdpi.com/2073-4409/11/24/4091

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https://www.mdpi.com/2073-4409/11/24/4091

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