NudC regulated Lis1 stability is essential for the maintenance of dynamic microtubule ends in axon terminals

Summary: In the axon terminal, microtubule stability is decreased relative to the axon shaft. The dynamic microtubule plus ends found in the axon terminal have many functions, including serving as a docking site for the Cytoplasmic dynein motor. Here, we report an unexplored function of dynein in mi...

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Bibliographic Details
Main Authors: Dane Kawano, Katherine Pinter, Madison Chlebowski, Ronald S. Petralia, Ya-Xian Wang, Alex V. Nechiporuk, Catherine M. Drerup
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422201344X