Deconvolution Tactics and Normalization in Renal Spatial Transcriptomics

The kidney is composed of heterogeneous groups of epithelial, endothelial, immune, and stromal cells, all in close anatomic proximity. Spatial transcriptomic technologies allow the interrogation of in situ expression signatures in health and disease, overlaid upon a histologic image. However, some s...

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Bibliographic Details
Main Authors: Ricardo Melo Ferreira, Benjamin J. Freije, Michael T. Eadon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.812947/full