An Assay Using Localized Surface Plasmon Resonance and Gold Nanorods Functionalized with Aptamers to Sense the Cytochrome-c Released from Apoptotic Cancer Cells for Anti-Cancer Drug Effect Determination

To determine the degree of cancer cell killing after treatment with chemotherapeutic drugs, we have developed a sensitive platform using localized surface plasmon resonance (LSPR) and aptamers to detect the extracellular cytochrome-c (cyto-c), a mitochondrial protein released from cancer cells for t...

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Bibliographic Details
Main Authors: Jacky Fong-Chuen Loo, Pui-Man Lau, Siu-Kai Kong, Ho-Pui Ho
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/8/11/338