Determining effective methadone doses for individual opioid-dependent patients.
BACKGROUND: Randomized clinical trials of methadone maintenance have found that on average high daily doses are more effective for reducing heroin use, and clinical practice guidelines recommend 60 mg/d as a minimum dosage. Nevertheless, many clinicians report that some patients can be stably mainta...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-03-01
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| Series: | PLoS Medicine |
| Online Access: | http://europepmc.org/articles/PMC1360079?pdf=render |