Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment

MicroRNAs (miRNAs) that regulate mRNA stability have been linked to amyloid production, tau phosphorylation, and inflammation in Alzheimer’s disease (AD). However, whether cerebral miRNA networks are dysregulated during the earliest stages of AD remains underexplored. We performed miRNA expression a...

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Bibliographic Details
Main Authors: Rebecca Bronwyn Weinberg, Elliott Jay Mufson, Scott Edward Counts
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Neuroscience
Subjects:
Gene Expression Regulation
MicroRNAs
Mild Cognitive Impairment
Sirtuin 1
frontal cortex
Alzheimer’s disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00430/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00430/full

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