Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

Deregulation of the translational machinery is emerging as a critical contributor to cancer development. The contribution of microRNAs in translational gene control has been established however; the role of microRNAs in disrupting the cap-dependent translation regulation complex has not been previou...

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Main Authors: Krystyna Mazan-Mamczarz, X Frank Zhao, Bojie Dai, James J Steinhardt, Raymond J Peroutka, Kimberly L Berk, Ari L Landon, Mariola Sadowska, Yongqing Zhang, Elin Lehrmann, Kevin G Becker, Rita Shaknovich, Zhenqiu Liu, Ronald B Gartenhaus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3907297?pdf=render