Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments

Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments

Background: Knee osteoarthritis (KOA), a chronic degenerative disease, is mainly characterized by destruction of articular cartilage and inflammatory reactions. At present, there is a lack of economical and effective clinical treatment. Zhuifeng Tougu (ZFTG) capsules have been clinically approved fo...

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Bibliographic Details
Main Authors: Xiaotong Xu, Naping Li, Yongrong Wu, Ke Yan, Yilin Mi, Nanxing Yi, Xuyi Tan, Gaoyan Kuang, Min Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
Zhuifeng tougu capsules
TLR4
NF-κB
knee osteoarthritis
inflammatory factors
innate immune
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.951860/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.951860/full

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