Development of an innovative 3D cell culture system to study tumour--stroma interactions in non-small cell lung cancer cells.

INTRODUCTION: We describe a novel 3D co-culture model using non-small cell lung cancer (NSCLC) cell lines in combination with lung fibroblasts. This model allows the investigation of tumour-stroma interactions and addresses the importance of having a more in vivo like cell culture model. METHODS: Au...

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Bibliographic Details
Main Authors: Arno Amann, Marit Zwierzina, Gabriele Gamerith, Mario Bitsche, Julia M Huber, Georg F Vogel, Michael Blumer, Stefan Koeck, Elisabeth J Pechriggl, Jens M Kelm, Wolfgang Hilbe, Heinz Zwierzina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963897?pdf=render