Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas

Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas

Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine-glutamate cycle is a way of controlling the production of gluta...

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Bibliographic Details
Main Authors: Filipa Martins, Luís G. Gonçalves, Marta Pojo, Jacinta Serpa
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
malignant gliomas
glutamine-glutamate cycle
CNS
cancer metabolism
metabolic adaptation
new metabolic-driven targets
Online Access:https://www.mdpi.com/2218-273X/10/10/1370

Internet

https://www.mdpi.com/2218-273X/10/10/1370

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