Ca2+ transfer to mitochondria: a spark of life in unexpected conditions

Ca2+ transfer to mitochondria: a spark of life in unexpected conditions

The inositol 1,4,5-triphosphate receptor (InsP3R)-mediated calcium (Ca2+) transfer to mitochondria is important to maintain mitochondrial respiration and bioenergetics in normal and cancer cells, even though cancer cells have defective oxidative phosphorylation (OXPHOS). Here, we discuss how tumor m...

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Bibliographic Details
Main Authors: Eduardo Silva-Pavez, Ulises Ahumada-Castro, Alenka Lovy, Julio Cesar Cárdenas
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Molecular & Cellular Oncology
Subjects:
calcium
oxphos
cell survival
autophagy
cancer
Online Access:http://dx.doi.org/10.1080/23723556.2020.1839341

Internet

http://dx.doi.org/10.1080/23723556.2020.1839341

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