Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice.

Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice.

The early events that shape the innate immune response to restrain pathogens during skin infections remain elusive. Methicillin-resistant Staphylococcus aureus (MRSA) infection engages phagocyte chemotaxis, abscess formation, and microbial clearance. Upon infection, neutrophils and monocytes find a...

Full description

Bibliographic Details
Main Authors: Stephanie L Brandt, Nathan Klopfenstein, Soujuan Wang, Seth Winfree, Brian P McCarthy, Paul R Territo, Lloyd Miller, C Henrique Serezani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6107286?pdf=render

Internet

http://europepmc.org/articles/PMC6107286?pdf=render

Similar Items