Pervasive translational regulation of the cell signalling circuitry underlies mammalian development

Gene expression is regulated at several levels, including through the modulation of protein translation. Here the authors find that translation control diversifies gene expression between developing tissues and regulates major signalling pathways through a complex landscape of upstream open reading...

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Bibliographic Details
Main Authors: Kotaro Fujii, Zhen Shi, Olena Zhulyn, Nicolas Denans, Maria Barna
Format: Article
Language:English
Published: Nature Portfolio 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14443